Publications
Publication highlights
Dedicated macrophages organize and maintain the enteric nervous system
Maria Francesca Viola, Marta Chavero-Pieres, Elodie Modave, Marcello Delfini, Nathalie Stakenborg, Maria Cuende Estévez, Naomi Fabre, Iris Appeltans, Tobie Martens, Katy Vandereyken, Hannah Theobald, Jens Van Herck, Philippe Petry, Simon Verheijden, Sebastiaan De Schepper, Alejandro Sifrim, Zhaoyuan Liu, Florent Ginhoux, Mohamad Azhar, Andreas Schlitzer, Gianluca Matteoli, Katrin Kierdorf, Marco Prinz, Pieter Vanden Berghe, Thierry Voet, Guy Boeckxstaens
Perivascular cells induce microglial phagocytic states and synaptic engulfment via SPP1 in mouse models of Alzheimer’s disease
Sebastiaan De Schepper, Judy Z Ge, Gerard Crowley, Laís SS Ferreira, Dylan Garceau, Christina E Toomey, Dimitra Sokolova, Javier Rueda-Carrasco, Sun-Hye Shin, Jung-Seok Kim, Thomas Childs, Tammaryn Lashley, Jemima J Burden, Michael Sasner, Carlo Sala Frigerio, Steffen Jung, Soyon Hong
Microglia modulate neurodegeneration in Alzheimer’s and Parkinson’s diseases
Tim Bartels, Sebastiaan De Schepper, Soyon Hong
Preoperative administration of the 5-HT4 receptor agonist prucalopride reduces intestinal inflammation and shortens postoperative ileus via cholinergic enteric neurons
Nathalie Stakenborg, Evelien Labeeuw, Pedro J Gomez-Pinilla, Sebastiaan De Schepper, Raymond Aerts, Gera Goverse, Giovanna Farro, Iris Appeltans, Elisa Meroni, Michelle Stakenborg, Maria Francesca Viola, Erika Gonzalez-Dominguez, Goele Bosmans, Yeranddy A Alpizar, Albert Wolthuis, Andre D’Hoore, Kim Van Beek, Simon Verheijden, Marleen Verhaegen, Rita Derua, Etienne Waelkens, Milena Moretti, Cecilia Gotti, Patrick Augustijns, Karel Talavera, Pieter Vanden Berghe, Gianluca Matteoli, Guy E Boeckxstaens
A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment
Hannah Van Hove, Liesbet Martens, Isabelle Scheyltjens, Karen De Vlaminck, Ana Rita Pombo Antunes, Sofie De Prijck, Niels Vandamme, Sebastiaan De Schepper, Gert Van Isterdael, Charlotte L. Scott, Jeroen Aerts, Geert Berx, Guy E. Boeckxstaens, Roosmarijn E. Vandenbroucke, Lars Vereecke, Diederik Moechars, Martin Guilliams, Jo A. Van Ginderachter, Yvan Saeys & Kiavash Movahedi
Self-maintaining gut macrophages are essential for intestinal homeostasis
Sebastiaan De Schepper, Simon Verheijden, Javier Aguilera-Lizarraga, Maria Francesca Viola, Werend Boesmans, Nathalie Stakenborg, Iryna Voytyuk, Inga Schmidt, Bram Boeckx, Isabelle Dierckx de Casterle, Veerle Baekelandt, Erika Gonzalez Dominguez, Matthias Mack, Inge Depoortere, Bart De Strooper, Ben Sprangers, Uwe Himmelreich, Stefaan Soenen, Martin Guilliams, Pieter Vanden Berghe, Elizabeth Jones, Diether Lambrechts, Guy Boeckxstaens
Non-classical tissue monocytes and two functionally distinct populations of interstitial macrophages populate the mouse lung
Joey Schyns, Qiang Bai, Cecilia Ruscitti, Coraline Radermecker, Sebastiaan De Schepper, Svetoslav Chakarov, Frédéric Farnir, Dimitri Pirottin, Florent Ginhoux, Guy Boeckxstaens, Fabrice Bureau, Thomas Marichal
Self-maintaining gut macrophages are essential for intestinal homeostasis
Sebastiaan De Schepper, Simon Verheijden, Javier Aguilera-Lizarraga, Maria Francesca Viola, Werend Boesmans, Nathalie Stakenborg, Iryna Voytyuk, Inga Schmidt, Bram Boeckx, Isabelle Dierckx de Casterlé, Veerle Baekelandt, Erika Gonzalez Dominguez, Matthias Mack, Inge Depoortere, Bart De Strooper, Ben Sprangers, Uwe Himmelreich, Stefaan Soenen, Martin Guilliams, Pieter Vanden Berghe, Elizabeth Jones, Diether Lambrechts, Guy Boeckxstaens
Strong upregulation of AIM2 and IFI16 inflammasomes in the mucosa of patients with active inflammatory bowel disease
Wiebe Vanhove, Paul M Peeters, Dominiek Staelens, Anica Schraenen, Jan Van der Goten, Isabelle Cleynen, Sebastiaan De Schepper, Leentje Van Lommel, Niki L Reynaert, Frans Schuit, Gert Van Assche, Marc Ferrante, Gert De Hertogh, Emiel FM Wouters, Paul Rutgeerts, Séverine Vermeire, Kris Nys, Ingrid Arijs
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